The first prophecy in the Bible is in Genesis 3:15, "I will put enmity between thee and the woman, and between thy seed and her seed; He shall bruise thy head, and thou shalt bruise his heel." This is known as the protoevangelium - the first gospel. The verse introduces two elements that are the basis of Christianity—the curse on mankind because of Adam and Eve's sin and God’s provision for a Savior from sin, the Messiah (anointed one), the one who would take the curse upon Himself.
Of course, we know these prophetic words were given to Adam and Eve after their disobeying God's one and only restrictive commandment of not eating from the tree of the knowledge of good and evil. For God had commanded Adam after He had placed him in the Garden of Eden, "Of every tree of the garden thou mayest freely eat: But of the tree of the knowledge of good and evil, thou shalt not eat of it: for in the day that thou eat thereof thou shalt surely die" (Genesis 2:16-17). We also know from Genesis 3 that the serpent (possessed by Satan) had lied and manipulated Eve into eating fruit from the tree. Eve, in turn, gave some to Adam, and he ate the forbidden fruit as well.
"The enmity - the hostility and hatred - of men and demons, between whom the warfare still continues, begins here. Evil angels and also wicked men are called serpents, and even a brood of vipers (Matthew 3:7), and they war against the people of God, the seed of the church, who are hated and persecuted by them, and so it has been ever since this affair in the Garden." {1}
Ultimately, however, the seed of the woman refers to Jesus Christ, who was born of a woman. And ultimately, the seed of the serpent (Satan) is the Antichrist (the beast), who will come at the end of the age. Satan's manipulations brought about the Lord's death through Judas, the Jewish Sanhedrin, and the Romans (although it was the Father's plan all along). Christ's death was considered (by God) only a "bruising of the heel" because He would be resurrected back to (eternal) life, whereas Satan and his offspring will spend eternity in the Lake of Fire, the second death.
The unholy trinity's (Satan, the Antichrist, and the false prophet) ultimate fate is found in Revelation 19 and 20. "And the beast was taken, and with him the false prophet that wrought miracles before him, with which he deceived them that had received the mark of the beast, and them that worshipped his image. These both were cast alive into a lake of fire burning with brimstone" (Revelation 19:20). One thousand years (plus "a little season") later, Satan will join the beast and the false prophet in the Lake of Fire. "And the devil that deceived them was cast into the lake of fire and brimstone, where the beast and the false prophet are, and shall be tormented day and night forever and ever" (Revelation 20:10).
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Of course, we know these prophetic words were given to Adam and Eve after their disobeying God's one and only restrictive commandment of not eating from the tree of the knowledge of good and evil. For God had commanded Adam after He had placed him in the Garden of Eden, "Of every tree of the garden thou mayest freely eat: But of the tree of the knowledge of good and evil, thou shalt not eat of it: for in the day that thou eat thereof thou shalt surely die" (Genesis 2:16-17). We also know from Genesis 3 that the serpent (possessed by Satan) had lied and manipulated Eve into eating fruit from the tree. Eve, in turn, gave some to Adam, and he ate the forbidden fruit as well.
"The enmity - the hostility and hatred - of men and demons, between whom the warfare still continues, begins here. Evil angels and also wicked men are called serpents, and even a brood of vipers (Matthew 3:7), and they war against the people of God, the seed of the church, who are hated and persecuted by them, and so it has been ever since this affair in the Garden." {1}
Ultimately, however, the seed of the woman refers to Jesus Christ, who was born of a woman. And ultimately, the seed of the serpent (Satan) is the Antichrist (the beast), who will come at the end of the age. Satan's manipulations brought about the Lord's death through Judas, the Jewish Sanhedrin, and the Romans (although it was the Father's plan all along). Christ's death was considered (by God) only a "bruising of the heel" because He would be resurrected back to (eternal) life, whereas Satan and his offspring will spend eternity in the Lake of Fire, the second death.
The unholy trinity's (Satan, the Antichrist, and the false prophet) ultimate fate is found in Revelation 19 and 20. "And the beast was taken, and with him the false prophet that wrought miracles before him, with which he deceived them that had received the mark of the beast, and them that worshipped his image. These both were cast alive into a lake of fire burning with brimstone" (Revelation 19:20). One thousand years (plus "a little season") later, Satan will join the beast and the false prophet in the Lake of Fire. "And the devil that deceived them was cast into the lake of fire and brimstone, where the beast and the false prophet are, and shall be tormented day and night forever and ever" (Revelation 20:10).

His Number is 666
The first prophecy in the Bible is in Genesis 3:15, "I will put enmity between thee and the woman, and between thy seed and her seed; He shall bruise thy head, and thou shalt bruise his heel." This is known as the protoevangelium - the first gospel. The verse introduces two elements that are the...
